Gerrit Cole struck out 15 batters over seven and two thirds shutout innings as the Astros held off the Rays 3-1 in Houston in Game Two of the ALDS.
Alex Bregman homered for Houston.
Carlos Correa and Martin Maldonado also drove in runs for the Astros.
The Rays loaded the bases against Roberto Osuna in the ninth but Will Harris came in to pick up the save for Houston, which takes a 2-0 series lead. Avisail Garcia drove in the lone run in the ninth for the Rays.
Blake Snell took the loss after allowing run over three and a third. Tampa Bay is one loss away from being eliminated.