New research from the Mayo Clinic shows that shows that puberty blockers can cause long term fertility and health problems for boys.
The study, which has not yet been peer-reviewed, analyzed more than 130,000 sperm cells from male children with gender dysphoria.
The researchers analyzed the testicular cells of boys who had been taking puberty blockers for anywhere from three months to 52 months, and compared them to cells of a control group who had not been on the blockers.
Among those on puberty blockers, the researchers identified mild to severe "sex gland atrophy," determining that the medications accelerated the aging and function of testicular cells.
The findings suggest that puberty blockers’ impacts may be permanent — disputing claims that such effects can be reversed.